Conversion of azathioprine into mercaptopurine and mercaptoimidazole derivatives in vitro and during immunosuppressive therapy

Aust J Exp Biol Med Sci. 1967 Dec;45(6):681-91. doi: 10.1038/icb.1967.68.
No abstract available

MeSH terms

  • Adult
  • Azathioprine / metabolism*
  • Azathioprine / therapeutic use
  • Chromatography, Gel
  • Glutathione / metabolism
  • Humans
  • Imidazoles / urine*
  • In Vitro Techniques
  • Kidney Transplantation
  • Male
  • Mercaptopurine / urine*
  • Spectrophotometry
  • Sulfhydryl Compounds / urine*
  • Transplantation Immunology
  • Transplantation, Homologous
  • Uric Acid

Substances

  • Imidazoles
  • Sulfhydryl Compounds
  • Uric Acid
  • Mercaptopurine
  • Glutathione
  • Azathioprine