Alpha-1-acetylmethadol and its N-demethylated metabolites have potent opiate action in the guinea pig isolated ileum

Life Sci. 1974 May 16;14(10):2011-7. doi: 10.1016/0024-3205(74)90417-2.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Acetates / metabolism
  • Acetates / pharmacology
  • Analgesics / metabolism
  • Analgesics / pharmacology*
  • Animals
  • Electric Stimulation
  • Guinea Pigs
  • Ileum / drug effects
  • Ileum / physiology*
  • Methadone / metabolism
  • Methadone / pharmacology*
  • Muscle, Smooth / drug effects
  • Muscle, Smooth / physiology*
  • Naloxone / pharmacology
  • Regression Analysis
  • Structure-Activity Relationship

Substances

  • Acetates
  • Analgesics
  • Naloxone
  • Methadone