Levomethadyl acetate. Prolonged duration of opioid effects, including cross tolerance to heroin, in man

JAMA. 1973 Oct 15;226(3):316-8. doi: 10.1001/jama.226.3.316.
No abstract available

MeSH terms

  • Acetates / pharmacology
  • Administration, Oral
  • Adult
  • Amino Alcohols / pharmacology
  • Amino Alcohols / therapeutic use*
  • Delayed-Action Preparations
  • Dimethylamines / pharmacology
  • Dimethylamines / therapeutic use
  • Dose-Response Relationship, Drug
  • Drug Tolerance
  • Heroin Dependence / drug therapy
  • Heroin* / administration & dosage
  • Heroin* / antagonists & inhibitors
  • Humans
  • Injections, Intravenous
  • Male
  • Middle Aged
  • Pupil / drug effects
  • Substance Withdrawal Syndrome / prevention & control
  • Substance-Related Disorders / drug therapy*
  • Time Factors

Substances

  • Acetates
  • Amino Alcohols
  • Delayed-Action Preparations
  • Dimethylamines
  • Heroin