Abstract
A detailed literature review of human and animal toxicity studies of acrolein is presented, and information gaps identified that call for further investigation. Specific recommendations are suggested for additional short-/long-term studies, including chemical disposition and cytogenetic investigations. Two bibliographies are provided indicating the scope of the review: (1) literature actually cited and (2) literature examined but not included.
MeSH terms
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Acrolein / adverse effects
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Acrolein / metabolism
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Acrolein / toxicity*
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Air Pollutants, Occupational / toxicity
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Aldehydes / toxicity*
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Animals
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Biotransformation
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Carcinogens
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Cardiovascular System / drug effects
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Chemical and Drug Induced Liver Injury / etiology
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Chromosome Aberrations / drug effects
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Environmental Pollutants / toxicity
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Eye Diseases / chemically induced
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Humans
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Intestinal Absorption
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Kidney Diseases / chemically induced
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Respiratory Tract Diseases / chemically induced
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Teratogens
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Water Pollutants, Chemical / toxicity
Substances
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Air Pollutants, Occupational
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Aldehydes
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Carcinogens
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Environmental Pollutants
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Teratogens
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Water Pollutants, Chemical
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Acrolein