Abstract
Morphine (0.5 mg/kg s.c.) and amphetamine (1 mg/kg s.c.) used in a two-compartment place preference test induced strong place preference when paired to the non-preferred environments. They did not modify preference under basal conditions but completely reversed morphine- and amphetamine-induced place preference. Pairing of haloperidol (0.2 mg/kg s.c.) to both environments also abolished the morphine-induced place preference.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amphetamine / antagonists & inhibitors*
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Animals
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Benzazepines / pharmacology*
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Conditioning, Operant / drug effects*
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Dopamine Antagonists*
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Drug Interactions
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Haloperidol / pharmacology
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Male
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Morphine / antagonists & inhibitors*
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Rats
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Rats, Inbred Strains
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Receptors, Dopamine / drug effects*
Substances
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Benzazepines
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Dopamine Antagonists
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Receptors, Dopamine
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Morphine
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Amphetamine
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Haloperidol