Effect of chloramphenicol administration in vivo on cytochrome P-450-dependent monooxygenase activities in liver microsomes from uninduced male rats

Biochem Pharmacol. 1988 Aug 1;37(15):3046-8. doi: 10.1016/0006-2952(88)90297-3.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Androstenedione / metabolism
  • Animals
  • Chloramphenicol / pharmacology*
  • Cytochrome P-450 Enzyme System
  • Dose-Response Relationship, Drug
  • In Vitro Techniques
  • Male
  • Microsomes, Liver / drug effects
  • Microsomes, Liver / enzymology*
  • Oxygenases / metabolism*
  • Progesterone / metabolism
  • Rats
  • Rats, Inbred Strains
  • Warfarin / metabolism

Substances

  • Androstenedione
  • Progesterone
  • Warfarin
  • Chloramphenicol
  • Cytochrome P-450 Enzyme System
  • Oxygenases