Phospholipid flippases

FEBS Lett. 1988 Jul 4;234(1):8-12. doi: 10.1016/0014-5793(88)81291-2.

Abstract

Protein mediated phospholipid translocation through membranes has been observed in rat liver endoplasmic reticulum and in the plasma membrane of erythrocytes as well as in a few other cell membranes. Lipid translocation in plasma membranes is ATP dependent and selectively accumulates aminophospholipids on the inner monolayers.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adenosine Triphosphate / pharmacology
  • Animals
  • Biological Transport
  • Carrier Proteins / blood
  • Carrier Proteins / physiology*
  • Cell Membrane / enzymology*
  • Erythrocyte Membrane / metabolism
  • Eukaryotic Cells / enzymology
  • Humans
  • Membrane Proteins*
  • Phospholipid Transfer Proteins*
  • Phospholipids / metabolism*
  • Prokaryotic Cells / enzymology

Substances

  • Carrier Proteins
  • Membrane Proteins
  • Phospholipid Transfer Proteins
  • Phospholipids
  • Adenosine Triphosphate