What is the nature of mecamylamine's antagonism of the central effects of nicotine?

Biochem Pharmacol. 1989 Oct 15;38(20):3391-7. doi: 10.1016/0006-2952(89)90106-8.

Authors

B R Martin¹, E S Onaivi, T J Martin

Affiliation

¹ Department of Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond.

PMID: 2684166
DOI: 10.1016/0006-2952(89)90106-8

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Brain / drug effects*
Humans
Mecamylamine / pharmacology*
Nicotine / antagonists & inhibitors*
Receptors, Nicotinic / drug effects*
Structure-Activity Relationship

Substances

Receptors, Nicotinic
Mecamylamine
Nicotine