Anthracyclines and heart failure

N Engl J Med. 2013 Mar 21;368(12):1154-6. doi: 10.1056/NEJMcibr1214975.

Author

Douglas B Sawyer¹

Affiliation

¹ Vanderbilt University Medical Center, Nashville, USA.

PMID: 23514294
DOI: 10.1056/NEJMcibr1214975

No abstract available

MeSH terms

Animals
Anthracyclines / adverse effects*
DNA Breaks, Double-Stranded
DNA Topoisomerases, Type II / deficiency
DNA Topoisomerases, Type II / genetics
DNA Topoisomerases, Type II / metabolism*
DNA-Binding Proteins / deficiency
DNA-Binding Proteins / genetics
DNA-Binding Proteins / metabolism*
Heart Failure / chemically induced*
Humans
Mice
Reactive Oxygen Species / metabolism*

Substances

Anthracyclines
DNA-Binding Proteins
Reactive Oxygen Species
DNA Topoisomerases, Type II