Abstract
The antihyperglycemic activity of the ethanolic extract of Butea monosperma (BMEE) was studied in glucose-loaded and alloxan-induced diabetic rats. Single dose treatment of BMEE (200 mg/kg, p.o.) significantly improved glucose tolerance and caused reduction in blood glucose level in alloxan-induced diabetic rats. Repeated oral treatment with BMEE (200 mg/kg/day) for 2 weeks significantly reduced blood glucose, serum cholesterol and improved HDL-cholesterol and albumin as compared to diabetic control group.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Blood Glucose / drug effects
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Butea / chemistry*
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Cholesterol / blood
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Cholesterol, HDL / analysis
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Cholesterol, HDL / drug effects
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Diabetes Mellitus / drug therapy
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Diabetes Mellitus, Experimental / drug therapy*
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Ethanol / chemistry
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Female
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Flowers / chemistry
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Glucose Tolerance Test
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Hypoglycemic Agents / isolation & purification
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Hypoglycemic Agents / pharmacology*
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Male
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Phytotherapy*
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Plant Extracts / administration & dosage
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Plant Extracts / pharmacology*
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Plants, Medicinal / chemistry
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Rats
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Rats, Wistar
Substances
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Blood Glucose
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Cholesterol, HDL
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Hypoglycemic Agents
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Plant Extracts
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Ethanol
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Cholesterol