[Optimization study on extraction technology of the seed of Ziziphus jujuba var. spinosa by orthogonal design with multi-targets]

Zhongguo Zhong Yao Za Zhi. 2005 May;30(10):753-5.
[Article in Chinese]

Abstract

Objective: To optimize extraction technology of the seed of Ziziphus jujuba var. spinosa with the targets of the total saponin, total jujuboside A and B and total flavonoids.

Method: In the method of one-way and orthogonal tests, ethanol concentration, amount of ethanol, extraction time and extraction times were the factors in orthogonal test, and each factor with three levels.

Result: Ethanol concentration and extraction times had significant effect on all the targets, other factors should be selected in accordance with production practice.

Conclusion: The best extraction technology is to extract for three times with 8 fold ethanol solution (60%), and 1.5 h each time.

Publication types

  • English Abstract

MeSH terms

  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Ethanol
  • Flavones / analysis
  • Plants, Medicinal / chemistry*
  • Saponins / analysis
  • Seeds / chemistry
  • Technology, Pharmaceutical / methods*
  • Ziziphus / chemistry*

Substances

  • Drugs, Chinese Herbal
  • Flavones
  • Saponins
  • Ethanol
  • jujuboside A