Abstract
The corpus-fundus of the urinary bladder of man and cat was studied in vitro with respect to type of beta-adrenergic receptors. In both species beta-adrenergic stimulation produced marked relaxation but species differences were apparent. In the cat bladder only beta1-receptors were found. In the human bladder the beta-receptors had neither beta1- nor beta2-characteristics. It is suggested that the beta-adrenergic receptors in the corpus-fundus of the human bladder are of a third type.
MeSH terms
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Acetylcholine / pharmacology
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Adrenergic beta-Agonists / pharmacology
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Albuterol / pharmacology
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Animals
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Butoxamine / pharmacology
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Cats
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Child
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Child, Preschool
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Drug Interactions
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Female
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Humans
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Isoproterenol / pharmacology
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Male
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Muscle Contraction / drug effects
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Norepinephrine / pharmacology
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Practolol / pharmacology
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Receptors, Adrenergic* / drug effects
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Receptors, Adrenergic, beta* / drug effects
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Urinary Bladder / drug effects
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Urinary Bladder / innervation*
Substances
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Adrenergic beta-Agonists
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Receptors, Adrenergic
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Receptors, Adrenergic, beta
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Butoxamine
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Isoproterenol
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Acetylcholine
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Albuterol
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Practolol
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Norepinephrine