Abstract
Recent advances in the molecular biology of excitatory amino acid receptors are reviewed. Evidence that drugs blocking the excitatory action of glutamate at the N-methyl-D-aspartate (NMDA) and non-NMDA receptors may be of clinical use in epilepsy, Parkinson's disease, cerebral ischaemia and trauma, acquired immune deficiency syndrome (AIDS) encephalopathy and neuropathic pain is summarized.
MeSH terms
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Amino Acids / physiology*
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Humans
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Nervous System / physiopathology
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Nervous System Diseases / physiopathology*
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Receptors, AMPA
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Receptors, Amino Acid
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Receptors, Cell Surface / physiology*
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Receptors, Glutamate
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Receptors, Kainic Acid
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Receptors, N-Methyl-D-Aspartate / physiology
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Receptors, Neurotransmitter / physiology
Substances
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Amino Acids
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Receptors, AMPA
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Receptors, Amino Acid
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Receptors, Cell Surface
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Receptors, Glutamate
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Receptors, Kainic Acid
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Receptors, N-Methyl-D-Aspartate
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Receptors, Neurotransmitter