Design, synthesis, and preclinical characterization of novel, highly selective indole estrogens

J Med Chem. 2001 May 24;44(11):1654-7. doi: 10.1021/jm010086m.
No abstract available

MeSH terms

  • Animals
  • Bone Density / drug effects
  • Cell Line
  • Estradiol Congeners / chemical synthesis*
  • Estradiol Congeners / chemistry
  • Estradiol Congeners / metabolism
  • Estradiol Congeners / pharmacology
  • Female
  • Indoles / chemical synthesis*
  • Indoles / chemistry
  • Indoles / metabolism
  • Indoles / pharmacology
  • Models, Molecular
  • Organ Size
  • Ovariectomy
  • Radioligand Assay
  • Rats
  • Structure-Activity Relationship
  • Transfection
  • Uterus / drug effects

Substances

  • Estradiol Congeners
  • Indoles