Physiological roles of G-protein-coupled receptor kinases revealed by gene-targeting technology

Trends Pharmacol Sci. 2000 Oct;21(10):364-7. doi: 10.1016/s0165-6147(00)01542-x.

Author

J Wess¹

Affiliation

¹ Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Building 8A, Bethesda, MD 20892-0810, USA.

PMID: 11050310
DOI: 10.1016/s0165-6147(00)01542-x

No abstract available

MeSH terms

Animals
Cyclic AMP-Dependent Protein Kinases / genetics*
Cyclic AMP-Dependent Protein Kinases / physiology
G-Protein-Coupled Receptor Kinase 5
Gene Targeting / methods*
Mice
Mice, Knockout
Phenotype
Protein Serine-Threonine Kinases / genetics*
Protein Serine-Threonine Kinases / physiology
Receptors, Muscarinic / physiology
beta-Adrenergic Receptor Kinases

Substances

Receptors, Muscarinic
Protein Serine-Threonine Kinases
Cyclic AMP-Dependent Protein Kinases
beta-Adrenergic Receptor Kinases
G-Protein-Coupled Receptor Kinase 5
Grk5 protein, mouse