Studies on the mechanism of action of the chlorinated dibenzo-p-dioxins and related compounds

Ann N Y Acad Sci. 1979 May 31:320:214-30. doi: 10.1111/j.1749-6632.1979.tb56603.x.
No abstract available

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Aryl Hydrocarbon Hydroxylases / biosynthesis
  • Aryl Hydrocarbon Hydroxylases / genetics
  • Binding Sites
  • Chick Embryo
  • Cytosol / metabolism
  • Dioxins / pharmacology*
  • Dose-Response Relationship, Drug
  • Enzyme Induction*
  • Female
  • Humans
  • Liver / drug effects
  • Liver / enzymology
  • Liver / pathology
  • Male
  • Methylcholanthrene
  • Mice
  • Mice, Inbred Strains
  • Models, Biological
  • Polychlorinated Biphenyls / pharmacology
  • Polychlorinated Biphenyls / toxicity
  • Polychlorinated Dibenzodioxins / analogs & derivatives
  • Polychlorinated Dibenzodioxins / pharmacology*
  • Polychlorinated Dibenzodioxins / toxicity
  • Structure-Activity Relationship

Substances

  • Dioxins
  • Polychlorinated Dibenzodioxins
  • Methylcholanthrene
  • Polychlorinated Biphenyls
  • Aryl Hydrocarbon Hydroxylases