Abstract
Fast neurotransmission in the brain is typically mediated by local actions of transmitters at ionotropic receptors within synaptic contacts. Recent studies now reveal that, in addition to point-to-point signaling, amino-acid transmitters mediate diffuse signaling at extrasynaptic metabotropic receptors.
MeSH terms
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Animals
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Brain / cytology
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Brain / physiology
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Glutamic Acid / physiology
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Receptors, GABA / physiology
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Receptors, Metabotropic Glutamate / physiology
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Synaptic Transmission / physiology*
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gamma-Aminobutyric Acid / physiology
Substances
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Receptors, GABA
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Receptors, Metabotropic Glutamate
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Glutamic Acid
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gamma-Aminobutyric Acid