Short CommunicationSpecies Differences in Intestinal Metabolic Activities of Cytochrome P450 isoforms between Cynomolgus Monkeys and Humans
References (21)
- et al.
The species differences of intestinal drug absorption and first-pass metabolism between cynomolgus monkeys and humans
J. Pharm. Sci.
(2009) - et al.
Characterization of cynomolgus monkey cytochrome P450 (CYP) cDNAs: is CYP2C76 the only monkey-specific CYP gene responsible for species differences in drug metabolism?
Arch. Biochem. Biophys.
(2007) - et al.
Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2 J2
Bioorg. Med. Chem. Lett.
(2006) - et al.
Marked species differences in the bioavailability of midazolam in cynomolgus monkeys and humans
Xenobiotica
(2006) - et al.
Prediction of the intestinal first-pass metabolism of CYP3A substrates in humans using cynomolgus monkeys
Drug Metab. Dispos.
(2010) - et al.
Effect of oral ketoconazole on intestinal first-pass effect of midazolam and fexofenadine in cynomolgus monkeys
Drug Metab. Dispos.
(2007) Human CYPs: in vivo and clinical aspects
Drug Metab. Rev.
(2002)Human cytochromes P450 associated with the phase 1 metabolism of drugs and other xenobiotics: A compilation of substrates and inhibitors of the CYP1, CYP2 and CYP3 families
Curr. Med. Chem.
(2003)- et al.
The human intestinal cytochrome P450 201“pie”
Drug Metab. Dispos.
(2006) - et al.
Human enteric microsomal CYP4F enzymes O-demethylate the antiparasitic prodrug pafuramidine
Drug Metab. Dispos.
(2007)
There are more references available in the full text version of this article.
Cited by (0)
Copyright © 2011 The Japanese Society for the Study of Xenobiotics. Published by Elsevier Ltd. All rights reserved.