Fundamental information that enhances our understanding of biospecific interactions can be obtained using a new analytical system based on biosensor technology. The functional characteristics of biospecific interaction, such as kinetics, affinity and binding position, are examined by label-free analysis of proteins in free solution binding to an immobilized ligand at a hydrophilic sensor surface.
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Malmqvist, M. Biospecific interaction analysis using biosensor technology. Nature 361, 186–187 (1993). https://doi.org/10.1038/361186a0
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DOI: https://doi.org/10.1038/361186a0
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