Abstract
The cytochalasins—a group of mould metabolites—inhibit movement and cytoplasmic cleavage in cultured cells. At higher doses they cause nuclear extrusion which may lead to total enucleation
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Aldridge, D. C., Armstrong, J. J., Speake, R. N., and Turner, W. B., Chem. Commun. (in the press).
Eagle, H., Science, 130, 432 (1959).
Carter, S. B., Exp. Cell Res., 42, 395 (1966).
Wolpert, L., Intern. Rev. Cytol, 10, 163 (1960).
Carter, S. B., Nature, 208, 1183 (1965).
Carter, S. B., Nature (p. 256 of this issue).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
CARTER, S. Effects of Cytochalasins on Mammalian Cells. Nature 213, 261–264 (1967). https://doi.org/10.1038/213261a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/213261a0
This article is cited by
-
Development of a micronucleus test using the EpiAirway™ organotypic human airway model
Genes and Environment (2023)
-
Development of reconstructed intestinal micronucleus cytome (RICyt) assay in 3D human gut model for genotoxicity assessment of orally ingested substances
Archives of Toxicology (2022)
-
Tools used to assay genomic instability in cancers and cancer meiomitosis
Journal of Cell Communication and Signaling (2022)
-
Phylogenetic analysis of Engleromyces sinensis and identification of cytochalasin D from culture
Mycological Progress (2021)
-
Cytokinesis defects and cancer
Nature Reviews Cancer (2019)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.