Rapid communicationInhibitory effects of an orexin-2 receptor antagonist on orexin A- and stress-induced ACTH responses in conscious rats
Section snippets
Acknowledgements
We thank Banyu Pharmaceutical Company (Japan) for providing orexin-2 receptor antagonist, OX2-RA; and Dr. T. Sakurai for providing an anti-orexin antibody. This work was supported in part by the 21st Century COE Program from the Ministry of Education, Culture, Sports, Science and Technology of Japan.
References (27)
- et al.
Differential distribution of orexin-A and orexin-B immunoreactivity in the rat brain and spinal cord
Peptides
(1999) - et al.
A selective orexin-1 receptor antagonist reduces food consumption in male and female rats
Regul. Peptides
(2000) - et al.
N-Acyl 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline: the first orexin-2 receptor selective non-peptidic antagonist
Bioorg. Med. Chem. Lett.
(2003) - et al.
Intracerebroventricular angiotensin II increases intraoral intake of water in rats
Peptides
(1998) - et al.
Effect of lateral cerebroventricular injection of the appetite-stimulating neuropeptide, orexin and neuropeptide Y, on the various behavioral activities of rats
Brain Res.
(1999) - et al.
Possible involvement of orexin in the stress reaction in rats
Biochem. Biophys. Res. Commun.
(2000) - et al.
Effects of restricted feeding on the activity of hypothalamic orexin (OX)-A containing neurons and OX2 receptor mRNA level in the paraventricular nucleus of rats
Regul. Peptides
(2002) - et al.
Neurons containing orexin in the lateral hypothalamic area of the adult rat brain are activated by insulin-induced acute hypoglycemia
Neurosci. Lett.
(1999) - et al.
Behavioural despair in rats: a new model sensitive to antidepressant treatments
Eur. J. Pharmacol.
(1978) - et al.
Centrally administered orexin-A activates corticotropin-releasing factor-containing neurons in the hypothalamic paraventricular nucleus and central amygdaloid nucleus of rats: possible involvement of central orexins on stress-activated central CRF neurons
Regul. Peptides
(2004)
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
Cell
(1998)
Orexin actions in hypothalamic paraventricular nucleus: physiological consequences and cellular correlates
Regul. Peptides
(2002)
Distribution of orexin receptor mRNA in the rat brain
FEBS Lett.
(1998)
Cited by (0)
Copyright © 2006 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.