TRPA1 expression in human lingual nerve neuromas in patients with and without symptoms of dysaesthesia
Section snippets
Acknowledgements
Funding provided by the Women Academic Returner's Programme, University of Sheffield. The TRPA1 antibody was donated by GlaxoSmithKline, UK.
References (32)
- et al.
TRPA1 receptor localisation in the human peripheral nervous system and functional studies in cultured human and rat sensory neuron
Neurosci. Lett.
(2008) - et al.
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin
Neuron
(2004) - et al.
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents
Cell
(2006) - et al.
Pungent products from garlic activate the sensory ion channel TRPA1
Proc. Natl. Acad. Sci. U.S.A.
(2005) Sex differences in pain
Behav. Brain Sci.
(1997)- et al.
Changes in vanilloid receptor 1 (TRPV1) expression following lingual nerve injury
Eur. J. Pain
(2007) - et al.
Vanilloid receptor 1 (TRPV1) expression in lingual nerve neuromas from patients with or without symptoms of burning pain
Brain Res.
(2007) - et al.
TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells
Nature
(2004) - et al.
NGF up-regulates TRPA1: implications for orofacial pain
J. Dent. Res.
(2007) - et al.
Increased TRPA1, TRPM8, and TRPV2 expression in dorsal root ganglia by nerve injury
Biochem. Biophys. Res. Commun.
(2007)
A review of age differences in the neurophysiology of nociception and the perceptual experience of pain
Clin. J. Pain
(2004)
Intact Adelta fibres up-regulate transient receptor potential A1 and contribute to cold hypersensitivity in neuropathic rats
Neuroscience
(2008)
Plasticity in intact A delta- and C-fibers contributes to cold hypersensitivity in neuropathic rats
Neuroscience
(2007)
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
Nature
(2004)
Antisense knock down of TRPA1, but not TRPM8, alleviates cold hyperalgesia after spinal nerve ligation in rats
Exp. Neurol.
(2006)
Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with adelta/c-fibers and colocalization with trk receptors
J. Comp. Neurol.
(2005)
Cited by (13)
Orofacial pain
2011, PainCitation Excerpt :Several risk factors for trigeminal neuralgia have been found, including multiple sclerosis [44,140] and hypertension [93]. Additional studies have reported changes in the expression of ion channels (eg, NaV1.3, 1.7, 1.8, TRPA1) in surgical biopsies collected from patients suffering from neuropathic orofacial pain [119,153]. Animal models of trigeminal neuropathic pain have been developed and include chronic constriction injury of the infraorbital nerve as well as transaction of the inferior alveolar nerve [3,177].
Localization and expression of TRPV1 and TRPA1 in the human oropharynx and larynx
2016, Neurogastroenterology and Motility
Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.