Clinical ResearchInterventional CardiologyImpact of Cytochrome P450 2C19 Loss-of-Function Polymorphism and of Major Demographic Characteristics on Residual Platelet Function After Loading and Maintenance Treatment With Clopidogrel in Patients Undergoing Elective Coronary Stent Placement
Interventional Cardiology
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Key Words
antiplatelet therapy
CYP2C19
platelet function
polymorphism
predictor
Abbreviations and Acronyms
ADP
adenosine diphosphate
BMI
body mass index
CART
classification and regression trees
CYP
cytochrome P450
DNA
deoxyribonucleic acid
MI
myocardial infarction
PCI
percutaneous coronary intervention
RPA
residual platelet aggregation
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This study was supported by a grant from the Herz-Zentrum, Bad Krozingen. Dr. Hochholzer was supported by the German Heart Foundation.
Copyright © 2010 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.