Synthesis and antitumor activity of benzils related to combretastatin A-4
Graphical abstract
Benzil derivatives related to combretastatin A-4 exhibit excellent antiproliferative and antimitotic activities by arresting the cell cycle in G2/M phase.
Section snippets
Acknowledgments
The authors gratefully acknowledge support of this project by CNRS and the MNSER for doctoral fellowships to C.M. and A.G.
References and notes (21)
Med. Chem. Rev.
(1996)et al.Med. Res. Rev.
(1998)et al.Expert Opin. Ther. Pat.
(2002)Curr. Med. Chem.
(2002)- et al.
J. Med. Chem.
(1991)et al.J. Med. Chem.
(1992) - et al.
J. Med. Chem.
(1980) - et al.
Prog. Cell Cycle Res.
(2003)et al.Pathol. Biol.
(2006)et al.Med. Res. Rev.
(2008) - et al.
Nat. Rev. Cancer
(2004)et al.Clin. Cancer Res.
(2005)Vascular-Targeted Therapies in Oncology
(2006) - et al.
J. Nat. Prod.
(1987)et al.Experientia
(1989) - et al.
Anti-Cancer Drug Des.
(1989)et al.Anti-Cancer Drugs
(1998) - et al.
J. Med. Chem.
(1995) - et al.
J. Med. Chem.
(1998) - et al.
Nat. Rev. Cancer
(2005)et al.Int. J. Exp. Pathol.
(2002)
There are more references available in the full text version of this article.
Cited by (103)
Iodine/DMSO-mediated one-pot access towards 1-aryl-2-(pyrazol-5-yl)ethane-1,2-diones via a domino reaction from functionalized pent-2-ene-1,5-diones
2024, Organic and Biomolecular ChemistryBenzils: A Review on their Synthesis
2022, Asian Journal of Organic ChemistryVisible-Light-Induced Photocatalytic Oxidative Decarboxylation of Cinnamic Acids to 1,2-Diketones
2021, Journal of Organic Chemistry
Copyright © 2008 Elsevier Ltd. All rights reserved.