Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Volume 1803, Issue 12, December 2010, Pages 1396-1408
Sigma-1 receptors amplify dopamine D1 receptor signaling at presynaptic sites in the prelimbic cortex
Under an Elsevier user license
open archive
Research Highlights
►Sigma-1 receptors amplify D1 receptor-induced PKA activation at presynaptic sites ►PKCβI plays an important role in the amplifying effect of the sigma-1 receptors ►Ca2+ influx via L-type Ca2+ channels plays an important role in the amplifying effect ►Activation of PKCβI by sigma-1 receptors is the upstream event of Ca2+ rise
Keywords
Sigma-1 receptors
Synaptosomes
Prelimbic cortex
D1 receptors
cAMP-dependent protein kinase
Ca2+ concentration
Cited by (0)
- 1
Co-first author.
Copyright © 2010 Elsevier B.V. All rights reserved.