Methylmalonate toxicity in primary neuronal cultures
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Keywords
malonate
Huntington's disease
striatum
calcium
inhibition of ATP production
free radicals
Abbreviations
EDTA, ethylenediaminetetra-acetate
HBS, HEPES-buffered saline
HEPES, N-2-hydroxyethylpiperazine-N′-2-ethanesulphonic acid
HPLC, high-pressure liquid chromotography
3-NPA, 3-nitropropionic acid
NMDA, N-methyl-d-aspartate
PBS, phosphate-buffered saline
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Copyright © 1998 IBRO. Published by Elsevier Ltd. All rights reserved.