Gastroenterology

Gastroenterology

Volume 116, Issue 5, May 1999, Pages 1246-1249
Gastroenterology

Editorials
Probiotics in inflammatory bowel disease: New insight to pathogenesis or a possible therapeutic alternative?

https://doi.org/10.1016/S0016-5085(99)70029-6Get rights and content

Abstract

GASTROENTEROLOGY 1999;116:1246-1249

References (37)

  • S Bengmark

    Econutrition and health maintenance. A new concept to prevent GI inflammation, ulceration and sepsis

    Clin Nutr

    (1996)
  • RB Sartor

    Enteric microflora in IBD: pathogens or commensal?

    Inflam Bowel Dis

    (1997)
  • L Sutherland et al.

    Double-blind, placebo controlled trial of metronidazole in Crohn's disease

    Gut

    (1991)
  • GR D'Haens et al.

    Early lesions of recurrent Crohn's disease caused by infusion of intestinal contents in excluded ileum

    Gastroenterology

    (1998)
  • RB Sartor

    Microbial factors in the pathogenesis of Crohn's disease, ulcerative colitis and experimental intestinal inflammation

  • R Duchmann et al.

    Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

    Clin Exp Immunol

    (1995)
  • A Macpherson et al.

    Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria

    Gut

    (1996)
  • RB Sartor

    Insights into the pathogenesis of inflammatory bowel disease provided by new rodent models of spontaneous colitis

    Iflam Bowel Dis

    (1995)
  • Cited by (191)

    • Effect of intestinal microbiome, antibiotics, and probiotics in the prevention and management of ulcerative colitis

      2022, Probiotics in the Prevention and Management of Human Diseases: A Scientific Perspective
    • Probiotics and prebiotics in ulcerative colitis

      2016, Best Practice and Research: Clinical Gastroenterology
      Citation Excerpt :

      It is assumed that an exaggerated mucosal immune response to commensal gut bacteria drives the inflammatory process in genetically susceptible individuals [4]. The role for the intestinal microbiota is supported by the finding that intestinal inflammation often occurs in anatomical areas with high bacterial numbers [5,6]. Furthermore, diversion of the fecal stream proximal to the inflamed area decreased disease activity in CD [7–10].

    • Lactobacillus pentosus var. plantarum C29 ameliorates memory impairment and inflammaging in a d-galactose-induced accelerated aging mouse model

      2014, Anaerobe
      Citation Excerpt :

      Many species reverse the disruptions in indigenous microbiota [16], inhibit carcinogenesis and induce non-specific activation of the host's immune system in humans and animal models [14]. Furthermore, the Lactobacilli have anti-diabetic [17] and anti-colitic effect [18,19]. Recently we found that Lactobacillus pentosus var.

    View all citing articles on Scopus

    Address requests for reprints to: Massimo Campieri, M.D., Unit for Inflammatory Bowel Disease, Department of Internal Medicine and Gastroenterology, Policlinico S. Orsola, Via Massarenti 9, 40138 Bologna, Italy. e-mail: [email protected]; fax: (39) 051-392538.

    View full text