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Cited by (27)
Effect of phosphorylation on antioxidant activities of pumpkin (Cucurbita pepo, Lady godiva) polysaccharide
2015, International Journal of Biological MacromoleculesDrying enhances immunoactivity of spent brewer's yeast cell wall β-d-glucans
2015, Journal of BiotechnologyCitation Excerpt :Literature data present options on simple chemical and physical modifications that may result in the increased immunological activity of spent brewer's yeast β-d-glucans. Chemical modification (phosphorylation or carboxylation) of glucose moieties at O-2 or O-6 positions leads to solubilization of the (1→3)-β-d-glucan (Williams et al., 1991; Lowman et al., 1998). Physical methods applied in baker's yeast β-d-glucan purification and drying have proven to affect their immunoactivity.
A NMR method to determine the anomeric specificity of glucose phosphorylation
2013, Bioorganic and Medicinal ChemistryCitation Excerpt :An important NMR paper by Peters and co-workers11 confirmed with the saturation transfer difference technique (STD-NMR) the earlier findings that α-d-glucose is the preferred binding partner of hexokinase, although it is known that β-d-glucose is phosphorylated faster kinetically. Two other papers used 31P NMR techniques12,13 to analyze these reactions. Several crystallographic investigations have determined the binding site of glucose in hexokinases but were not able to address the anomeric specificity from a structural point of view.14–16
Preparation, chain conformation and anti-tumor activities of water-soluble phosphated (1 → 3)-α-d-glucan from Poria cocos mycelia
2011, Carbohydrate PolymersCitation Excerpt :As shown in Fig. 2, 31P NMR spectrum of the phosphated derivative exhibited an intense and multi-signal peak for phosphorus resonance in the region of 0.4–1.3 ppm. The results confirmed that phosphate groups were bound to the molecular chain, and indicated that phosphate groups were located in several different magnetic environments ascribed to the substitution at different position such as C-6, C-2 or C-4 (Granja et al., 2001b; Lowman et al., 1998). In addition, the second small peak was observed at −9.8 ppm, suggesting that another type of phosphate group was present in the phosphated derivative.
Synthesis of (1→6)-β-D-glucosamine hexasaccharide, a potential antitumor and immunostimulating agent
2002, Tetrahedron Letters