Technique for stabilizing the striation pattern in maximally calcium-activated skinned rabbit psoas fibers

A procedure was developed for stabilizing the striation pattern of fully activated skinned rabbit psoas fibers. Inhomogeneities of the striation pattern that develop during the rise in tension and also during isometric steady state are completely reversible by this procedure. The striation pattern can be stabilized for approximately 2 h. During this period isometric tension and speed of isotonic shortening decrease less than 10–20% of their initial values.