Estrogenic and postcoital anticonceptive activity in rats of butin isolated from Butea monosperma seed
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Cited by (47)
Estrogenic flavonoids and their molecular mechanisms of action
2023, Journal of Nutritional BiochemistryCitation Excerpt :Bavachin and isobavachin, prenylated flavanones, and other prenylflavones exhibit estrogenic activity [141]. Butin isolated from the seeds of Butea monosperma was reported to be estrogenic [142]. Isoxanthohumol, which can be found in beer and traditional Chinese medicine, is weakly estrogenic or not estrogenic, whereas its O-demethylated product, 8-prenylnaringenin, is a strong estrogen [143–146].
Traditional Chinese medicine and Ayurvedic care during pregnancy
2022, Fertility, Pregnancy, and WellnessInhibitory effect of Rhus verniciflua Stokes extract on human aromatase activity; Butin is its major bioactive component
2014, Bioorganic and Medicinal Chemistry LettersPotential antifertility agents from plants: A comprehensive review
2012, Journal of EthnopharmacologyCitation Excerpt :Literature survey of the cited plants confirmed that Abrus precatorius (Ross, 2005; Okoko et al., 2010), Acalypha indica (Hafez, 1970; Shivayogi et al., 1999), Ailanthus excelsa (Ravichandran et al., 2007), Ananas comosus (Bhaduri et al., 1968; Garó et al., 1970; Näf-Müller and Willhalm, 1971), Aristolochia bracteolata (Natraj et al., 2007), Azadirachta indica (Riar et al., 1991; Sinha et al., 1984a,b), Bambusa vulgaris (Yakubu and Bukoye, 2009), Embelia ribes (Radhakrishnan and Alam, 1975; Garg and Garg, 1978; Prakash, 1981), Hibiscus rosa-sinensis (Pakrashi et al., 1986; Vasudeva and Sharma, 2008), Plumbago zeylanica (Premakumari et al., 1977; Chowdhury et al., 1982; Edwin et al., 2009), Vicoa indica (Dhall and Dogra, 1988; Rao et al., 1996) potent antifertility effects. Among plant derived constituents, Abridine (Zia-ul-Haque et al., 1983a,b), Acacetin (Hiremath et al., 1990; Hiremath and Rao, 1990), Aristolochic acid (Chakrabarty et al., 1987), Butin (Bhargava, 1986), Embelin (Radhakrishnan and Alam, 1975; Krishnaswamy and Purushothaman, 1980a), Ferujol (Singh et al., 1985; Prakash et al., 1991), Momorcharins (Yeung et al., 1986), Oleanolic acid-3β-glucoside (Pillai et al., 1982), Plumbagin (Premakumari et al., 1977; Kini et al., 1997); β-sitosterol (Pakrashi and Basak, 1976), Vicolides B & D (Mohana et al., 1984; Susan et al., 1985, 1986; Alam et al., 1989) etc. have shown potential antifertility effects. Some plants have shown opposite effects in male and females.
Butin decreases oxidative stress-induced 8-hydroxy-2′-deoxyguanosine levels via activation of oxoguanine glycosylase 1
2009, Chemico-Biological InteractionsCitation Excerpt :One such DNA repair enzyme, 8-oxoguanine DNA glycosylase 1 (OGG1), repairs these oxidative lesions via a base-excision repair (BER) pathway in mammals. Butin (7,3′,4′-trihydroxydihydroflavone) was isolated from several medicinal herbs [10–13] and has biological activities such as skin-whitening and anti-implantation activity [14,15]. We have recently demonstrated that butin protects cells against H2O2-induced damage of cellular components including DNA [16].
Abortifacient potentials of the aqueous extract of Bambusa vulgaris leaves in pregnant Dutch rabbits
2009, ContraceptionCitation Excerpt :An agent that can disrupt pregnancy could be of obvious interest in human fertility control [4]. Some of these agents can be used as a contraceptive method specifically as a postcoital contraceptive [34,35]. Various parameters evaluated in this study are useful indices to assess the potentials of a plant as anti-implantation and estrogenic/anti-estrogenic agents as well as the presence of abortifacient activities and its mechanism of action.