Alcohol's effect on body temperature: Hypothermia, hyperthermia or poikilothermia?
References (53)
- et al.
Effect of taurine on some pharmacological properties of ethanol
Pharmac. Biochem. Behav.
(1978) - et al.
Calcium enhancement of alcohol and drug-induced sleeping time in mice and rats
Pharmac. Biochem. Behav.
(1980) - et al.
Physical dependence on ethanol: Rate of ethanol clearance from the blood and effect of ethanol on body temperature in rats
Toxic, appl. Pharmac.
(1978) Hypothermia after acute ethanol and benzyl alcohol administration
Life Sci.
(1973)- et al.
Peptide-neurotransmitter in-teractions influencing ethanol tolerance
Drug Alcohol Depend.
(1979) - et al.
The effect of ethanol on the ability of guinea-pigs to survive severe cold
Forensic Sci.
(1977) - et al.
Role of serotonin in tolerance to ethanol and barbiturates: Evidence for a specific vs. non-specific concept of tolerance
Drug Alcohol Depend.
(1979) - et al.
Cross-tolerance between ethanol and morphine with respect to their hypothermic effects
Eur. J. Pharmac.
(1979) Impairment of thermoregulation, food and water intakes in the rat after hypothermic injections of 5, 6-dihydroxytryptamine
Brain Res.
(1975)- et al.
Thermoregulation in the rat: Deficits following 6-OHDA injections in the hypothalamus
Pharmac. Biochem. Behav.
(1978)
Feeding and temperature responses in the unrestrained rat after injections of cholinergic and aminergic substances into the cerebral ventricles
Physiol. Behav.
Hypothalamic Na4 and Ca1+ ions and temperature set-point: New mechanisms of action of a central or peripheral thermal challenge and intrahypothalamic 5-HT, NE, PGE, and pyrogen
Brain Res. Bull.
Antagonism of depressant activity of ethanol by DH-524; a comparative study with be-megride, doxapram and d-amphetamine
The effect of alcohol on carbohydrate metabolism: Carbohydrate metabolism in alcoholics
Feeding re-sponses of rats with dorsomedial hypothalamic lesions given ip 2DG or glucose
Am. J. Physiol.
Calcium gluconate and phenoxybenzamine: Paradoxi-cal modification of ethanol dependence in mice
Inhibition of food intake in the rat following complete absorption of glucose delivered into the stomach, intestine or liver
J. Physiol.
Amphibia
Ethanol withdrawal: Altered ambient temperature selection in rats
Alcoholism: Clin. expl Res.
Exchange, control, and regulation
Rapid development of tolerance to the hypothermic effect of ethanol in mice
J. Pharmac. exp. Ther.
Effect of body temperature on acute ethanol toxicity
Life Sci.
Ethanol: Modification of acute intoxication by divalent cations
Science
Effect of alcohol on thermal balance of man in cold water
Can. J. Physiol. Pharmac.
Effect of p-Chlorophenylalanine on the acquisition of tolerance to the hypothermic effects of ethanol
Psychopharmacology
Cited by (108)
Effect of paclitaxel content in the DHP107 oral formulation on oral bioavailability and antitumor activity
2018, Journal of Drug Delivery Science and TechnologyCitation Excerpt :However, chemotherapy-related fatigue could be diminished by changing the formulation of paclitaxel. Ethanol is reported to produce a dose-dependent reduction in colonic temperature when orally administered to rats at doses of 2 and 4 g/kg [35]. In this study, 0.8 g/kg of ethanol was infused intravenously to mice when Taxol® was administered to mice at a dose of 12.5 mg/kg.
The thermoregulation system and how it works
2018, Handbook of Clinical NeurologyCitation Excerpt :Hence, in states with a wide interthreshold zone, Tb is regulated with a greatly reduced precision and strongly depends on Ta. The states with a narrow interthreshold zone are called homeothermic; the states with a wide interthreshold zone are poikilothermic (Myers, 1981); compare these terms with the thermoregulation types shown in Figure 1.1. Third, the balance point of thermoregulation can be elevated, which signifies fever, or decreased, which corresponds to anapyrexia.
Binge alcohol consumption 18 h after induction of sepsis in a mouse model causes rapid overgrowth of bacteria, a cytokine storm, and decreased survival
2017, AlcoholCitation Excerpt :Hypothermia is also observed in some human sepsis patients, and these patients typically have a poorer outcome than patients who exhibit a fever response (Laupland et al., 2004; Wang et al., 1989). Some of the effects of hypothermia on inflammation have been reported to be reversible (Johnson, Haddix, Pohlman, & Verrier, 1995; Myers, 1981). However, it was not clear whether alcohol-induced hypothermia was one of the major factors that induced the suppression of the innate immune response to bacterial infection in our previous studies of the effects of alcohol on resistance to sepsis (Bhatty et al., 2011; Pruett et al., 2004; Pruett, Fan, et al., 2010).
Activation of NLRP3 inflammasome by cholesterol crystals in alcohol consumption induces atherosclerotic lesions
2017, Brain, Behavior, and ImmunityCitation Excerpt :This observation was significant and clinically relevant because blood alcohol levels of >60% (v/v) would likely be lethal to humans. Importantly, alcohol related poikilothermic effects, a characteristic rise and fall of body temperature in alcoholism (Myers, 1981) may impact CCs formation in real life. For example, hyperthermia commonly observed in alcohol withdrawal in humans with chronic heavy alcohol consumption may promote cholesterol solubility, whereas subsequent hypothermia when withdrawal has subsided may crystallize cholesterol.
Binge drinking: Ethanol effects on ventilation at rest. Toxicokinetics and toxicodynamics studies in rat
2014, Toxicologie Analytique et CliniqueAttenuation of MDMA-induced hyperthermia by ethanol in rats depends on ambient temperature
2007, European Journal of Pharmacology