Research sectionFormulation effect on the dermal bioavailability of isothiazolone biocide
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Cited by (19)
Effects of chemical agent injections on genotoxicity of wastewater in a microfiltration-reverse osmosis membrane process for wastewater reuse
2013, Journal of Hazardous MaterialsCitation Excerpt :In order to inhibit microbial growth in RO system without damaging RO membrane, non-oxidizing biocides are used in RO systems instead of oxidizing biocides. One of the most common non-oxidizing biocide is Kathon biocide, it is composed by 5-chloro-2-methyl-4-isothiazoline-3-one (CMIT) and 2-methyl-4-isothiazoline-3-one (MIT) (Fig. 3) [12]. Certain isothiazolone-3-one biocides achieve its biocidal activity by the reaction with thiol-containing enzymes [13,14].
Atmospheric pressure gas chromatography coupled to quadrupole-time of flight mass spectrometry as a powerful tool for identification of non intentionally added substances in acrylic adhesives used in food packaging materials
2012, Journal of Chromatography ACitation Excerpt :The accurate masses of the fragments allowed to confirm the identification of the candidates proposed initially. This finding is very relevant, as these compounds are suspected to cause contact allergy in humans [18,19] and to be cytotoxic [20,21]. Therefore it is crucial to study their migration from the adhesive used to make the food packaging to the food, because in case these compounds migrate it would contaminate the food.
Retrospective exposure assessment in a chemical research and development facility
2012, Environment InternationalRisk assessment of contact allergens
1998, American Journal of Contact DermatitisProduct safety, risk assessment, and responsible care in the biocide chemical industry
1996, Regulatory Toxicology and Pharmacology