Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
Volume 995, Issue 1, 16 March 1989, Pages 36-41
Regular paperMucus proteinase inhibitor: a fast-acting inhibitor of leucocyte elastase
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Physics-driven identification of clinically approved and investigation drugs against human neutrophil serine protease 4 (NSP4): A virtual drug repurposing study
2020, Journal of Molecular Graphics and ModellingCitation Excerpt :NSPs are therefore associated with various inflammatory diseases like chronic obstructive pulmonary disease, cystic fibrosis, acute respiratory distress syndrome, rheumatoid arthritis [31] and non-infectious inflammatory diseases like arthritis, bullous pemphigoid and glomerulonephritis [33,34]. In order to control the activity of these proteases a number of physiological and non-physiological inhibitors for NSPs regulation has been identified and reported [35–57]. NSP4 is found to be highly conserved among the vertebrate species from bony fish to humans and originate earlier than the other NSPs [5].
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Copyright © 1989 Published by Elsevier B.V.