Reinstatement of extinguished cocaine-taking behavior by cocaine and caffeine
References (26)
- et al.
Discriminative stimulus properties of cocaine: Neuropharmacological characteristics as derived from stimulus generalization experiments
Pharmacol. Biochem. Behav.
(1979) - et al.
Adenosine receptors in the central nervous system: Relationship to the central actions of methylxanthines
Life Sci.
(1981) - et al.
Potentiation of cocaine's discriminative effects by caffeine: A time effect analysis
Pharmacol. Biochem. Behav.
(1990) - et al.
Drug-induced reinstatement of extinguished self-administration behavior in monkeys
Pharmacol. Biochem. Behav.
(1975) - et al.
Behavioral interaction between cocaine and caffeine: A drug discrimination analysis in rats
Pharmacol. Biochem. Behav.
(1989) - et al.
Methylxantine discrimination in the rat: Possible benzodiazepine and adenosine mechanisms
Pharmacol. Biochem. Behav.
(1985) - et al.
Effect of caffeine on cocaine locomotor stimulant activity in rats
Pharmacol. Biochem. Behav.
(1986) - et al.
Caffeine and the central nervous system: Mechanisms of action, biochemical, metabolic and psychostimulant effects
Brain Res. Rev.
(1992) - et al.
Integrating systematic cue exposure with standard treatment in recovering drug dependent patients
Addict. Behav.
(1990) - et al.
Heterogeneity of binding sites for N-ethylcarboxamidol [3H] in rat brain: Effects of N-ethylmaleimide
Brain Res.
(1986)
Differential effects of isolation housing on the conditioned place preference produced by cocaine and amphetamine
Pharmacol. Biochem. Behav.
Cocaine-induced place preference conditioning: Lack of effects of neuroleptics and 6-hydroxydopamine lesions
Brain Res.
Mechanism of action of caffeine
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Intravenous and oral caffeine self-administration in rats
2019, Drug and Alcohol DependenceSex differences in reinstatement of cocaine-seeking with combination treatments of progesterone and atomoxetine
2016, Pharmacology Biochemistry and BehaviorCitation Excerpt :Broadly, these results are consistent with the majority of the literature showing a sex difference where females self-administer more cocaine than males (see Anker and Carroll, 2011). Reinstatement of cocaine-seeking after a CAF priming injection has been well-established (Regier et al., 2014; Weerts and Griffiths, 2003; Green and Schenk, 2002; Schenk et al., 1996; Worley et al., 1994), yet sex-specific effects of CAF as a priming agent have not been studied. The present study was the first to show that females had enhanced responding, compared to males, on the cocaine-associated lever after a priming injection of CAF (5 mg/kg).
Behavioral Pharmacology of Caffeine
2013, Tea in Health and Disease PreventionStimulation of adenosine receptors in the nucleus accumbens reverses the expression of cocaine sensitization and cross-sensitization to dopamine D <inf>2</inf> receptors in rats
2012, NeuropharmacologyCitation Excerpt :Within the striatum, postsynaptic adenosine receptor subtypes co-localize with specific dopamine receptor subtypes in the medium spiny neurons where they appear to antagonize postsynaptic dopamine signaling (Bertran-Gonzalez et al., 2009; Ferre et al., 1994a, 1994b, 1999; Gines et al., 2000; Hakansson et al., 2006; Svenningsson et al., 1998). Emergent findings show that A1 and A2A receptors may play a critical role in regulating cocaine-induced behavioral responses (Bachtell and Self, 2009; Filip et al., 2006; Green and Schenk, 2002; Knapp et al., 2001; O'Neill et al., 2012; Poleszak and Malec, 2002b; Worley et al., 1994). Most relevant is a recent study demonstrating that systemic administration of an A2A agonist decreased, while administration of an A2A antagonist increased, cocaine-induced locomotor sensitization in rats (Filip et al., 2006).
Caffeine increases the motivation to obtain non-drug reinforcers in rats
2012, Drug and Alcohol DependenceCitation Excerpt :More importantly, despite limited success demonstrating primary reinforcement by caffeine (Atkinson and Enslen, 1976) there have been several studies demonstrating that caffeine increases the reinforcing effects of other drugs. Caffeine administration increases alcohol drinking (Kunin et al., 2000), cocaine self-administration (Schenk et al., 1994), and reinstates extinguished cocaine-seeking behavior (Green and Schenk, 2002; Worley et al., 1994). Prior exposure to caffeine also increases the psychomotor stimulant effects of amphetamine (Palmatier et al., 2003; Simola et al., 2006), nicotine (Celik et al., 2006; Palmatier et al., 2003) and cocaine (Schenk et al., 1994) as well as the primary reinforcing effects of cocaine (Horger et al., 1991) and nicotine (Jones and Griffiths, 2003; Shoaib et al., 1999).
Effect of kappa-opioid receptor agonists U69593, U50488H, spiradoline and salvinorin A on cocaine-induced drug-seeking in rats
2009, Pharmacology Biochemistry and Behavior