Stimulus properties of a new designer drug: 4-methylaminorex (“U4Euh”)
References (15)
- et al.
Stimulus properties of 1-(3,4-methylenedioxyphenyl)-2-aminopropane (MDA) analogs
Pharmacol. Biochem. Behav.
(1988) - et al.
Methcathinone: A new and potent amphetamine-like agent
Pharmacol. Biochem. Behav.
(1987) - et al.
A fatality involving U4Euh, a cyclic derivative of phenylpropanolamine
J. Forensic Sci.
(1988) - et al.
The central locomotor stimulatory activity and acute toxicity of the ephedrine and norephedrine isomers in mice
J. Pharmacol. Exp. Ther.
(1967) Schedules of controlled substances;
Placement of (±)cis-4-methylaminorex into Schedule I: April 13, 1989
(1989)Probit analysis
(1952)Psychoactive phenylisopropylamines
Cited by (24)
Pharmacological characterization of the aminorex analogs 4-MAR, 4,4′-DMAR, and 3,4-DMAR
2019, NeuroToxicologyCitation Excerpt :In contrast, substance users report effects of 4-MAR to be more like methamphetamine than MDMA (Erowid, 2002), consistent with the present in vitro pharmacological data. In vivo studies with 4-MAR in rats and primates also revealed amphetamine-like psychostimulant properties (Batsche et al., 1994; Glennon and Misenheimer, 1990; Mansbach et al., 1990). Furthermore, 4-MAR and its isomers produced conditioned place preference, which was mediated via dopamine D1 and D2 receptors (Meririnne et al., 2005) in line with its dopaminergic action.
Rewarding properties of the stereoisomers of 4-methylaminorex: Involvement of the dopamine system
2005, Pharmacology Biochemistry and BehaviorDetection and assay of cis- and trans-isomers of 4-methylaminorex in urine, plasma and tissue samples
2001, Forensic Science InternationalRecreational use of aminorex and pulmonary hypertension
2000, ChestCitation Excerpt :Officials for the Drug Enforcement Administrationconfirmed that the cis-isomer of 4-methyl-aminorex (street names,“U-4-E-uh” [pronounced euphoria] or “ice”) has appeared onthe clandestine market as a “designer” drug alternative tomethamphetamine (street name, “crank”). 4-Methyl-aminorex (Fig 1), which has gained attention due to its potential as a centralstimulant of abuse and because of the ease with which it issynthesized, was recently classified as a schedule Isubstance.3 The drug is generally synthesized from theover-the-counter diet pill phenylpropanolamine HCl and is smoked as thefree base or the HCl salt.
Stimulus properties of some analogues of 4-methylaminorex
1995, Pharmacology, Biochemistry and BehaviorEvaluation of the abuse liability of aminorex
1994, Drug and Alcohol Dependence