ArticleStress ulcer susceptibility and depression in Wistar Kyoto (WKY) rats
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2019, Physiology and BehaviorDanger and safety signals independently influence persistent pathological avoidance in anxiety-vulnerable Wistar Kyoto rats: A role for impaired configural learning in anxiety vulnerability
2019, Behavioural Brain ResearchCitation Excerpt :The Wistar-Kyoto (WKY) rat is used as a model of anxiety-vulnerability. This rat strain demonstrates a behaviorally-inhibited profile, as they show reduced exploration of novel social [20,21] and non-social situations [22–24], and a behaviorally inhibited temperament is a risk factor for developing anxiety disorders [25,26]. Interestingly, these rats also show rapid acquisition of and increased tendencies to avoid relative to Sprague Dawley (SD) rats [27–29].
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