Elsevier

Life Sciences

Volume 28, Issue 5, 2 February 1981, Pages 493-497
Life Sciences

Current concepts
V. Liquid chromatography with electrochemical detection for plasma norepinephrine and epinephrine

https://doi.org/10.1016/0024-3205(81)90142-9Get rights and content

Abstract

One of the most significant advances in catecholamine methodology in recent years has been the development of the electrochemical detector in combination with liquid chromatography.

In this report the practicability of this system for the routine quantitative determination of norepinephrine and epinephrine in plasma is described. The method has been found to be of particular value in evaluating the effect of alpha adrenergic agonists on norepinephrine and epinephrine levels in the plasma of dogs.

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    Present address: School of Pharmacy, University of Southern California, Los Angeles, California 90033.

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