Short communication
In vitro effects of melatonin on HCG stimulation of steroid accumulation by rabbit ovarian follicles

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Abstract

Isolated rabbit ovarian follicles were incubated with HCG and/or melatonin, serotonin, 5-hydroxy-dl-tryptophan or N-acetyl serotonin. Melatonin alone significantly decreased the accumulation of steroids elicited by HCG stimulation. Follicles did not bind labelled melatonin whereas the specific binding of [125I]-HCG was 4.11 pmol per mg protein.

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