Comparison of rat and mouse circadian rhythm of cholesterol-7α-hydroxylase activity

doi:10.1016/0022-4731(79)90518-1

Journal of Steroid Biochemistry

Volume 10, Issue 6, June 1979, Pages 647-651

https://doi.org/10.1016/0022-4731(79)90518-1 Get rights and content

Abstract

The circadian rhythm of the cholesterol-7α-hydroxylase activity previously described in the rat, is also detectable in various strains of mice. Nevertheless, its amplitude is much less pronounced. In both species, the phenomenon seems to be controlled by the glucocorticoids. The limited circadian variation in the mouse is more likely linked to (a) the reduced sensitivity of the mouse enzyme to the glucocorticoids and (b) the slightly longer biological half-life of mouse cholesterol-7α-hydroxylase.

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Comparison of rat and mouse circadian rhythm of cholesterol-7α-hydroxylase activity

Abstract

Biochimie

J. Lipid. Res.

Biochim. biophys. Acta

J. biol. Chem.

Rythme circadien de la cholestérol-7α-hydroxylase chez le rat

C.R. Acad. Sci. (Paris)

Rat liver cholesterol-7α-hydroxylase. III. New results about its circadian rhythm

Eur. J. Biochem.