Rapid communicationBrain dialysis in conscious rats reveals an instantaneous massive release striatal dopamine in response to MPP+
References (4)
- et al.
Dopaminergic toxicity after the stereotaxic administration of the 1-methyl-4-phenylpyridinium ion (MPP+) to rats
Neurosci. Lett.
(1985) - et al.
Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice
Science
(1984)
There are more references available in the full text version of this article.
Cited by (97)
Effects of the Parkinsonian toxin MPP<sup>+</sup> on electrophysiological properties of nigral dopaminergic neurons
2014, NeuroToxicologyCitation Excerpt :Taken together, our results strongly suggest that MPP+ displaces vesicular DA, which interacts with D2 autoreceptors after extracellular release. This indirect action is consistent with previous reports that MPP+ rapidly releases striatal DA in vivo (Rollema et al., 1986; Pileblad et al., 1984) and in striatal brain slices (Markstein and Lahaye, 1984; Schmidt et al., 1984). Although a previous study has shown that MPP+ also releases DA from cultured dopaminergic neurons (Lotharius and O’Malley, 2000), cultured neurons develop numerous axons and axon terminals (Jomphe et al., 2005), making it difficult to distinguish whether DA originated from these terminals or from cell bodies and dendrites.
Sleep disorders in Parkinson's disease: The contribution of the MPTP non-human primate model
2009, Experimental NeurologyAcute and Chronic Administration of 1-Methyl-4-Phenylpyridinium
2008, Parkinson's DiseaseAcute and chronic administration of 1-methyl-4-phenylpyridinium
2008, Parkinson's Disease: Molecular and Therapeutic Insights From Model SystemsAcute perfusion of BMAA in the rat's striatum by in vivo microdialysis
2006, Toxicology Letters
Copyright © 1986 Published by Elsevier B.V.