Short communication
Intrathecal morphine in mice: A new technique

https://doi.org/10.1016/0014-2999(80)90515-4Get rights and content

Abstract

A simple, rapid technique for intrathecal injections by lumbar puncture in unanesthetized mice is described. Intrathecal [3H]morphine base was not found in significant quantitities in either the midbrain or forebrain. Submicrogram quantities of morphine sulfate induced Straub tail response and tail-flick analgesia. These effects were dose related and antagonized by subcutaneous naloxone.

References (9)

There are more references available in the full text version of this article.

Cited by (1791)

View all citing articles on Scopus
View full text