Regular paperThe rotating rodent: A two component system?
References (24)
- et al.
Relation of contraversive turning to unilateral release of dopamine from the nigrostriatal pathway in rats
Exptl. Neurol.
(1971) - et al.
Turning behaviour induced by electrical stimulation of the nigro-neostriatal system of the rat
Exptl. Neurol.
(1975) A sensitive method for spectophotoflurometric assay of catecholamines
Intern. J. Neuropharmacol.
(1964)- et al.
Stereotyped and circling behaviour induced by dopaminergic agonists after lesions of the midbrain raphé nuclei
European J. Pharmacol.
(1974) - et al.
The relationship between striatal and mesolimbic dopamine dysfunction and the nature of circling responses following 6-hydroxydopamine and electrolytic lesions of the ascending dopamine systems of rat brain
Brain Res.
(1976) - et al.
Non-specific supersensitivity of striatal dopamine receptors after 6-hydroxydopamine lesion of the nigrostriatal pathway
J. Pharmacol.
(1976) - et al.
The roles of noradrenaline and dopamine in contraversive circling behaviour seen after unilateral electrolytic lesions of the locus coeruleus
J. Pharmacol.
(1976) - et al.
Turning in circles: the neuropharmacology of rotation
Life Sci.
(1976) - et al.
Circling behaviour in rats with 6-hydroxydopamine or electrolytic nigral lesions
European J. Pharmacol.
(1976) Unilateral 6-hydroxydopamine lesions of nigrostriatal or mesolimbic dopamine-containing terminals and the drug-induced rotation of rats
Brain Res.
(1975)
Selective 6-OHDA-induced destruction of mesolimbic dopamine neurons: abolition of psychostimulant-induced locomotor activity in rats
European J. Pharmacol.
(1976)
Circling behaviour produced by unilateral lesions in the region of the locus coeruleus
Brain Res.
(1975)
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The macrocyclic lactones ivermectin and moxidectin show differential effects on rotational behavior in the 6-hydroxydopamine mouse model of Parkinson's disease
2020, Behavioural Brain ResearchCitation Excerpt :The MFB lesion model depletes DA in the dorsal and ventral striatum and leads to cell death in both the SNpc and VTA. The destruction of both the mesolimbic and nigrostriatal pathways induces rotational behavior [37–40]. While rotation behavior is focused on dopamine receptor activation it is important to also consider the potential role of other neurotransmitters and dopaminergic projections other than the nigrostriatal pathway.
The rotational model and microdialysis: Significance for dopamine signalling, clinical studies, and beyond
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2005, Movement Disorders
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Present address and correspondence: Department of Pharmacology, Medical School, University of Bristol, Bristol BS8 1 TD, England.
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