Inactivation of microsomal Ca2+-ATPase by 2-chloroethylethyl sulfide
References (12)
- et al.
Molecular basis for mustard-induced vesication
Fundam. Appl. Toxicol.
(1985) - et al.
Cystamine induces toxicity in hepatocytes through the elevation of cytosolic Ca2+ and the stimulation of a nonlysosomal proteolytic system
J. Biol. Chem.
(1986) - et al.
The effects of nitrogen mustard (HN2) on activities of the plasma membrane of PC6A mouse plsmacytoma cells
Biochem. Pharmacol.
(1982) - et al.
Ion transport ATPases as targets for free radical damage
Biochem. Pharmacol.
(1993) Toxicology of mustard gas
Trends Pharmacol. Sci.
(1991)- et al.
Concentration- and dose-related effects of sulphur mustard on human epidermal keratinocyte function
Toxicol. In Vitro
(1992)
Cited by (8)
Correlation among phenyltins molecular properties, degradation and cellular influences on Bacillus thuringiensis in the presence of biosurfactant
2016, Biochemical Engineering JournalCitation Excerpt :For example, Na+/K+-ATPase activity in the gill and brain of Cirrhinus mrigala under mercuric chloride stress was found to be significantly decreased [27]. Exposure to 2-chloroethylethyl sulfide also led to a dose-dependent decrease in Ca2+/Mg2+-ATPase activity by alkylating the enzyme [28]. Therefore, the ATPase activity may be used as an index to determine tolerable levels of contaminants [27].
Treatment of keratin intermediate filaments with sulfur mustard analogs
2007, Biochemical and Biophysical Research CommunicationsCitation Excerpt :Our results leave open the possibility that SM destruction of the kIF network is the mechanism behind the vesicant action of SM. The concentration of CEES and MEC we have used is higher than used in some tissue culture models [11,16,17] but it is similar to the concentrations used in live animal studies [13,14,24,25,29–31]. The specific, limited, and reversible modification of keratins using CE-MTS reveals that a relatively small number of modifications interfers with proper filament assembly.
Progress in development of drugs against sulfur mustard-induced injury
2010, Chinese Journal of Pharmacology and ToxicologyRelative molecular similarity in selected chemical carcinogens and the nucleoside triphosphate chain
2003, Pharmacology and ToxicologyGene expressions in Jurkat cells poisoned by a sulphur mustard vesicant and the induction of apoptosis
2002, British Journal of PharmacologyIL-1-related cytokine responses of nonimmune skin cells subjected to CEES exposure with and without potential vesicant antagonists
2000, In Vitro and Molecular Toxicology: Journal of Basic and Applied Research