Research reportCocaine: evidence for supraspinal, dopamine-mediated, non-opiate analgesia
References (39)
- et al.
Differential effects of chronic partial myelotomies on monoamine levels in cat spinal cord
Brain Research
(1987) - et al.
Vagino-cervical probing elevates blood pressure and induces analgesia by separate mechanisms
Physiol. Behav.
(1987) - et al.
Sympathomimetics as analgesics: effects of methoxamine, methamphetamine, metaraminol and norepinephrine
Life Sci.
(1964) - et al.
The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats
Pain
(1977) Opiate and opioid peptide effects on brain stem neurons: relevance to nociception and antinociceptive mechanisms
Pain
(1982)- et al.
Corticotropin-releasing factor (CRF) produces analgesia in humans and rats
Brain Research
(1987) SCH 23390 — the first selective dopamine D-1 antagonist
Eur. J. Pharmacol.
(1983)- et al.
Stereo-specific potentiation of opiate analgesia by cocaine: predominant role of noradrenaline
Pain
(1987) - et al.
The effect of systemic cocaine on spinal nociceptive reflex activity in the rat
Brain Research
(1988) - et al.
Cardiovascular effects of cocaine in anesthetized and conscious rats
Life Sci.
(1987)
Cocaine stimulates adrenocorticotropin (ACTH) secretion through a corticotropin-releasing factor (CRF)-mediated mechanism
Brain Research
Inhibition of uptake of tritiated catecholamines by antidepressants and related drugs
Eur. J. Pharmacol.
ICV-CRH potently affects behavior without altering antinociceptive responding
Life Sci.
The systemic administration of local anesthetics produces a selective depression of C-afferent fiber evoked activity in the spinal cord
Pain
Pain sensitivity and opioid activity in genetically and experimentally hypertensive rats
Brain Research
Disruption of cocaine and heroin self-administration following kainic acid lesions of the nucleus accumbens
Pharmacol. Biochem. Behav.
Cocaine: neurophysiological effects on bulboreticular projections neurons
Soc. Neurosci. Abstr.
Review: D1 dopamine receptor — the search for a function: a critical evaluation of the D1/D2 dopamine receptor classification and its functional implications
Synapse
A method of determining loss of pain sensation
J. Pharmacol. Exp. Ther.
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Herbal biomolecules acting on central nervous system
2022, Herbal Biomolecules in Healthcare ApplicationsRole of dopamine D2-like receptors within the ventral tegmental area and nucleus accumbens in antinociception induced by lateral hypothalamus stimulation
2015, Behavioural Brain ResearchCitation Excerpt :In the second part of this study, it was revealed that blockade of the D2-like dopamine receptors within the VTA and NAc inhibited the antinociception induced by chemical stimulation of the LH in the tail-flick test. These findings were consistent with previous studies which showed that selective D2-like dopamine receptor antagonists systemically attenuated the analgesia induced by systemic amphetamine, morphine and cocaine in the formalin test [38,39]. Moreover, the antinociceptive effects of apomorphine were blocked by the D2-like receptor antagonist, eticlopride [40].
Orexin A induced antinociception in the ventral tegmental area involves D1 and D2 receptors in the nucleus accumbens
2014, Pharmacology Biochemistry and BehaviorInteraction between the dopaminergic and opioidergic systems in dorsal hippocampus in modulation of formalin-induced orofacial pain in rats
2014, Pharmacology Biochemistry and BehaviorCitation Excerpt :This interesting data may indicate that dopamine has no effect during the blockade of opioid receptors. Several lines of evidence point to the role of dopamine neurons in antinociception (Lin et al., 1989; Magnusson and Fisher, 2000). Antinociceptive effects induced by conditioning noxious stimulation were reversed by dopamine receptor blockade (Gear et al., 1999).