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Are periaqueductal gray and dorsal raphe the foundation of appetitive and aversive control? A comprehensive review
2019, Progress in NeurobiologyInvolvement of spinal release of α-neo-endorphin on the antinociceptive effect of TAPA
2013, PeptidesCitation Excerpt :In contrast, the selective μ2-opioid receptor antagonists d-Pro2-endomorphin-1 and d-Pro2-Tyr-W-MIF-1 did not alter the TAPA-induced antinociception (Fig. 3C and D) at doses that significantly suppressed the endomorphin-1-induced antinociception [18,27]. To elucidate the involvement of μ1-opioid receptors in the TAPA-induced antinociception, CXBK mice whose μ1-opioid receptors were naturally reduced [11,12] and the parental strain C57BL/6ByJ mice were used. Groups of CXBK mice and C57BL/6ByJ mice were treated i.t. with TAPA (0.375–12 pmol), and the antinociception induced by TAPA was measured at 10 min after the treatment.
Opioid receptor subtypes: Fact or artifact?
2011, British Journal of Anaesthesia
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