Biochemical and Biophysical Research Communications
Endothelin-1 and endothelin-3 stimulate calcium mobilization by different mechanisms in vascular smooth muscle
References (26)
- et al.
Atheroscler
(1990) - et al.
Biochem. Biophys. Res. Commun
(1991) - et al.
Biochem. Biophys. Res. Commun
(1991) - et al.
Biochem. Biophys. Res. Commun
(1989) - et al.
J. Biol. Chem
(1990) - et al.
J. Biol. Chem
(1991) - et al.
J. Biol. Chem
(1985) - et al.
J. Biol. Chem
(1990) - et al.
Cell
(1985) - et al.
FEBS LETTS
(1990)
J. Biol. Chem
J. Biol. Chem
Biochem. Biophys. Res. Commun
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