Discrimination of three parallel pathways of lactate transport in the human erythrocyte membrane by inhibitors and kinetic properties
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2011, Medical HypothesesCitation Excerpt :Mature human erythrocytes are non-nucleated cells and lose all cellular organelles, including mitochondria [1]. Instead, they produce energy carrier ATP from glucose by glycolysis that ends with l-lactic acid production secreted from the cells by monocarboxylate carriers [1,2]. In these cells, 0.1–0.4% of glucose is, however, metabolized via methylglyoxal produced non-enzymatically from glycolytic intermediate dihydroxyacetone-phosphate [3].
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