EditorialHistamine and the human heart: The other receptor system
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Histamine H<inf>2</inf> Receptor Antagonists, Left Ventricular Morphology, and Heart Failure Risk: The MESA Study
2016, Journal of the American College of CardiologyKounis syndrome secondary to amoxicillin use in an asthmatic patient
2011, International Journal of CardiologyCitation Excerpt :Once the mast cell–antibody–antigen complex is formed, a complex series of events occurs that eventually leads to cell degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Experimental and clinical evidence indicates that the human heart can be the site and the primary target of anaphylaxis [9]. It is known that histamine acts via four different histamine receptors all of which contribute to the severity of the allergic myocardial damage.
Mechanisms of allergic reactions occurring during anaesthesia
2011, Annales Francaises d'Anesthesie et de ReanimationImpact of Blockade of Histamine H<inf>2</inf> Receptors on Chronic Heart Failure Revealed by Retrospective and Prospective Randomized Studies
2006, Journal of the American College of CardiologyCitation Excerpt :Indeed, the increase of mast cells have been observed in the hearts of patients with hypertrophy (22), dilated cardiomyopathy, ischemic cardiomyopathy (23), and ischemia/reperfusion (24), and the infarction-related coronary arteries (25). Furthermore, histamine is present in high concentrations in cardiac tissues in most animal species, including humans (10,26,27), and its release from cardiac stores and the subsequent actions on the heart may be of importance in the pathophysiology of heart disease. These lines of evidence agree with the present observation that the blockade of histamine H2receptors in failing hearts has an impact on the pathophysiology of CHF.
Histamine, Mast Cells, and Heart Failure. Is There a Connection?<sup>*</sup> * Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.
2006, Journal of the American College of CardiologyKounis syndrome (allergic angina and allergic myocardial infarction): A natural paradigm?
2006, International Journal of Cardiology