Summary and Conclusions
Daily marijuana smoking has been clearly shown to have adverse effects on pulmonary function and produce respiratory symptomatology (cough, wheeze, and sputum production) similar to that of tobacco smokers. Based on the tobacco experience, decrements in pulmonary function may be predictive of the future development of chronic obstructive pulmonary disease (COPD). However, in the absence of α-l-antitrypsin deficiency, the habitual marijuana-only smoker would likely have to smoke 4–5 joints per day for a span of at least 30 yr in order to develop overt manifestations of COPD.
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Van Hoozen, B.E., Cross, C.E. Marijuana. Clinic Rev Allerg Immunol 15, 243–269 (1997). https://doi.org/10.1007/BF02737700
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DOI: https://doi.org/10.1007/BF02737700