Abstract
The effects of guanabenz on some copper containing amine oxidases are described. Guanabenz ‘in vitro’ inhibits pig plasma benzylamine oxidase with a IC50 M 5.1±0.8×10−6 M. It also inhibits pig kidney diamine oxidase and rat liver mitochondrial monoamine oxidase at higher concentrations. The significance of this property of guanabenz is discussed.
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Banchelli, G., Bertocci, B., Raimondi, L. et al. Guanabenz as inhibitor of copper-containing amine oxidases. Agents and Actions 18, 46–48 (1986). https://doi.org/10.1007/BF01987979
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DOI: https://doi.org/10.1007/BF01987979